HPLC Method Development Training Course
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Course Title: HPLC Analytical Method Development for Pharmaceutical Analysis
This HPLC training course in analytical method development is aimed at analysts who have been performing HPLC analysis and troubleshooting HPLC for approximately 6 months to 1 year, and who wish to develop HPLC methods for pharmaceuticals. The training is delivered using live web-based training, where the MTS trainer and the learner communicate over the internet. The HPLC training course is split into 8 sessions, each of approximately 45 to 60 minutes in length. The timing for the delivery of the sessions is arranged to suit the learner. For example, a popular choice is to deliver two sessions in a day over a total period of four days. MTS will make every effort to fit in with the schedule that suits you.
Every attendee on a MTS course is asked to fill in a brief survey on their previous experience and training expectations to ensure that the training is optimised for their learning needs.
The standard cost for this HPLC training course, charged per person, is GBP £600 + VAT.
Synopsis
HPLC analytical method development is a critical process when using HPLC for pharmaceutical analysis. Methods need to separate the desired components satisfactorily, they need to generate the required results, and they must be reproducible and robust so that they can be used time after time without problems. Often method development training courses contain very interesting material and create a good impression but when the analyst returns to the lab they find they don’t know where to start!
The selection of suitable HPLC conditions to achieve a desired separation is often both confusing and time consuming. This HPLC training course provides a 5 step strategy which can be followed to develop HPLC methods. The strategy combines in depth theory on method development together with an efficient and straightforward approach. Analysts will learn how to develop a HPLC method that is suitable for their application. Attendees are encouraged to bring along examples of method development challenges for discussion during the training. Refer to the full course description for details of the agenda on each of the 8 sessions of the training.
Learning Objectives:
After taking this course the learner will be able to:
Define the objectives for the development of a HPLC analytical method.
Effectively assess all the available relevant information relating to the desired method.
Understand the effects of the structure of the analyte, e.g. pKa.
Select and prepare a suitable sample or samples to be used for the method development.
Select suitable scouting conditions to find a suitable column and mobile phase system.
Understand the differences between HPLC columns.
Perform measurements which indicate the degree of separation for a method, e.g. resolution.
Understand the effects of mobile phase composition and temperature on separation.
Optimise the chromatographic conditions to result in the best possible separation.
Use computer modelling as an aid to method development.
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This course is supported in e-MTS, the virtual environment for learning provided by Mourne Training Services to support our training courses.
MTS also provides expert advice on your in-house training programmes; online, pre-prepared training courses for in-house use; and training books on topics such as HPLC and analytical method validation.
