Resources

MTS offers range of resources to assist you in the application of analytical chemistry, primarily relating to the analysis of pharmaceuticals and biopharmaceuticals.

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Free Webinars

We offer webinars on a range of topics related to the training courses that we provide. They act as learning opportunities combined with taster sessions for our services.

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Free download:

HPLC Calculator

Includes calculations for quantity of mobile phase to prepare, equilibration time, buffer preparation and more...

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We are delighted to offer a range of concise and useful articles on a wide range of topics relating to analytical chemistry and primarily the analysis of pharmaceuticals and biopharma. Browse the contents list to identify the Brief Guides most relevant to your work.

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Videos

Informative videos on HPLC instruments and also validation of methods for biotherapeutics.

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e-Newsletter

Keep in touch with MTS!

We'll send you the latest resources as they become available and recent MTS news.

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Free download:

Aide Mémoire for Method Transfer

A tool to help you assess your methods for potential problems prior to transfer.

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Blog

The MTS blog contains posts on a range of topics related to analytical chemistry such as: HPLC (troubleshooting, method development, etc.), method validation and transfer, and compliance issues, to name but a few.

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LinkedIn Articles

Articles on chemical analysis topics from our consultant, Oona McPolin, on topics such as OOS, mass balance, method validation, etc.

Books from MTS

MTS offers books on topics relating to the chemical analysis of pharmaceuticals. The books are written by Oona McPolin, the MTS trainer and consultant. They provide practical and current information. The topics available are introductory HPLC and method validation, both applied to pharmaceutical analysis.

Shipping information:

Postage and packing is FREE to UK and Ireland addresses and is very reasonably priced for other locations at only £3.50 GBP for Europe and £5.50 GBP for the rest of the world. The shipping time depends on your location and is typically less than 14 days from the date of the order, but due to the current coronavirus situation it could be significantly longer.

Contact us if you would like a quotation for multiple copies of either or both books, or if you have any questions.

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An Introduction to HPLC for Pharmaceutical Analysis

"A brief well-written guide and resource to assist the analyst in the use of HPLC in a pharmaceutical analysis environment."

Chemistry World, Royal Society of Chemistry

Title: An Introduction to HPLC for Pharmaceutical Analysis

Cost: GBP £29.00

Author: Oona McPolin

ISBN: 978-0-9561528-0-0

Format: Paperback, 210 x 300mm (A4), 148 pages

Publisher: Mourne Training Services Ltd

This book is aimed at those who are new to HPLC. Whether you are a new starter in an analytical laboratory, an experienced scientist new to HPLC, a recent graduate, or a student, it provides an invaluable guide about how HPLC is actually used when analysing pharmaceuticals.

A thorough discussion of the stationary phase enabling the reader to make sense of the many parameters used to describe a HPLC column.
Practical advice and helpful hints for the preparation and use of mobile phase.
A complete overview of each of the different components which together make up a HPLC system.
A description of the contents of a typical HPLC analytical method and how to interpret these.
A step-by-step guide on how to follow a method and set up a HPLC analysis.
A discussion of system suitability criteria and how to interpret the values obtained during an analysis.
Explanation of the common methods of calibration and quantification used for pharmaceutical analysis.

A complimentary copy of this book is provided for attendees on the e-Learning course, 'Basic HPLC for Pharmaceutical Analysis'.

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Validation of Analytical Methods for Pharmaceutical Analysis

"A nicely written handbook on how to perform validation of methods used in pharmaceutical analysis."

Chemistry World, Royal Society of Chemistry

Title: Validation of Analytical Methods for Pharmaceutical Analysis

Cost: GBP £29.00

Author: Oona McPolin

ISBN: 978-0-9561528-1-7

Format: Paperback, 210 x 300mm (A4), 152 pages

Publisher: Mourne Training Services

A full review of the available regulatory guidelines on validation and in particular, those from the International Conference on Harmonisation (ICH). Sections of the guideline, Q2(R1), have been reproduced in this book with the kind permission of the ICH Secretariat.

Thorough discussion of each of the validation characteristics: Specificity; Linearity; Range; Accuracy; Precision; Detection Limit; Quantitation Limit; Robustness; System Suitability; plus practical tips on how they may be studied.
What to include in a validation protocol, with advice on the experimental procedure to follow and selection of appropriate acceptance criteria.
How to interpret and calculate the results of a validation study, including the use of suitable statistical calculations.
A fully explained case study demonstrating how to plan a validation study, what to include in the protocol, experiments to perform, setting acceptance criteria, interpretation of the results and reporting the study.

View errataView errata

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Free Webinars

Our free webinars provide a taster of our

live online training courses. They are delivered by our trainer,

Oona McPolin, an expert in analytical chemistry applied to pharmaceuticals and biopharmaceuticals with over 25 years of experience. Our webinars are learning opportunities for all attendees and as such a Certificate of Attendance is available on request. We are always open to ideas for new webinars, let us know if you would like to make a suggestion! Places on webinars are limited and if after you sign up, you find that you can no longer attend for some reason, it would be greatly appreciated if you could let us know.

Currently Available Webinars:

Upcoming:

No webinars planned at this time. Check back soon!

Recordings:

Tips for Successful Analytical Method Transfer

Wednesday 4th November 2020 at 15:30 GMT/16:30 CET/10:30 EST

Coming soonComing soon

Strategies for HPLC Method Development

Tuesday 4th August 2020 at 15:00 BST/16:00 CEST/10:00 EDT

Webinar RecordingWebinar Recording

Where do the Acceptance Criteria in Method Validation Come From?

Wednesday 12th August 2020 at 15:00 BST/16:00 CEST/10:00 EDT

Webinar RecordingWebinar Recording

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Free HPLC Calculator

The MTS HPLC calculator is in the form of an Excel spreadsheet comprised of 7 worksheets which correspond to useful HPLC related calculations. The calculator was developed to support our HPLC training courses, 'How to Run HPLC Methods', 'How to Troubleshoot HPLC' and 'How to Develop HPLC Methods - Part 1 & 2'. It has been downloaded hundreds of times by users all over the world. If you have any requests or feedback then please let us know.

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HPLC Calculator from Mourne Training Services Ltd

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The calculations provided are as follows:

Column Equilibration
For how long do you need to equilibrate a column before it is ready to use?

Void Volume
Calculates the void volume and estimates the retention time of t0 (often referred to as the solvent front).

Pressure Converter
Change pressure units between the most commonly used units, e.g. psi to bar

Mobile Phase Buffer Strength
Performs the conversion from millimoles (mM) and %w/w to a mass and volume.

Mobile Phase Quantity - Isocratic
Works out how much mobile phase you will need to prepare for an isocratic analysis.

Mobile Phase Quantity - Gradient
Works out how much mobile phase you will need to prepare for a gradient analysis (one of the most popular!).

Method Development

Accompanies our HPLC method development courses to provide a simple way to convert a single gradient scouting run into a prediction of best conditions for initial method development, and predict whether an isocratic or a gradient approach will be most suitable.

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Videos

The videos below are designed to provide helpful information on analytical chemistry topics. They are also available on the MTS YouTube channel. Please feel free to use them in your training programmes.

HPLC Instruments

A Brief Guide to HPLC Instruments

This video describes the different parts of a HPLC instrument. A picture of how the whole system operates is built up gradually by introducing each part and defining the role that it plays. The video is a sample of our training and in particular, the type of training materials used in our e-Learning course, 'Basic HPLC for Pharmaceutial Analysis'.

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Validating 'Bio' methods

Why are 'Bio' Test Methods So Tricky to Validate?

This video provides an overview of some of the problems associated with validation of test methods for biopharmaceuticals. These issues are explored in detail in the MTS course, 'Validation and Transfer of Methods for Biopharmaceutical Analysis'.

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Free Aide Mémoire for Method Transfer

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Aide mémoire for method transfer from Mourne Training Services Ltd

The purpose of this aide mémoire is to provide a list of method features that may be important to consider during a transfer. It provides a convenient means to identify any potential issues and record the findings.

The aide mémoire was developed for the training course, ‘Validation & Transfer of Methods for Pharmaceutical Analysis’.

This pdf document is intended as an aid for the review of an analytical method prior to transfer to another laboratory. It is recognised that it is not an exhaustive list (hence the name 'aide mémoire' instead of 'checklist') and it is intended that it will be updated from time to time. Feedback and ideas for new additions are always welcome.

This is a free tool and as such MTS does not accept any liability in connection with the use of this aide mémoire.

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MTS e-Newsletter

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When you are signed up to our e-newsletter you will receive an occasional email which contains MTS news and also new resources, such as articles about topics relating to chemical analysis, when they become available.

Your details are never passed on to any third parties and you can unsubscribe at any time.

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Resources

Books

Free Webinars

HPLC Calculator

A Brief Guide to...

Videos

e-Newsletter

Aide Mémoire for Method Transfer

Blog

LinkedIn Articles

Books from MTS

Shipping information:

An Introduction to HPLC for Pharmaceutical Analysis

Validation of Analytical Methods for Pharmaceutical Analysis

Free Webinars

Currently Available Webinars:

Upcoming:

Recordings:

Tips for Successful Analytical Method Transfer

Strategies for HPLC Method Development

Where do the Acceptance Criteria in Method Validation Come From?

Free HPLC Calculator

Simply fill in and submit the form to download your FREE HPLC calculator.

Videos

A Brief Guide to HPLC Instruments

Why are 'Bio' Test Methods So Tricky to Validate?

Free Aide Mémoire for Method Transfer

Simply fill in and submit the form to download your FREE aide mémoire for method transfer.

MTS e-Newsletter

Sign up to our free e-newsletter: